Friday, 24 March 2023

65/F with Altered sensorium secondary to hyperthyroidism

[13/3/2023]
A 65 year old female pt presented to Gen surg opd with complaints/of
 swelling in front of neck since 2years
 C/o pain in swelling since 20 days

Pt was apparently asymptomatic 2 years back then she developed a swelling in neck which is insidious in onset, gradually progressive to present size of 9x6cm. Associated with pain (pricking type), 
non radiating, 
no aggrevating or relieving factors
H/0 difficulty in swallowing since 6 months.
H/o difficulty in breathing since 6 months
No h/o hoarseness of voice
No other swelling in the neck
No other h/o s/o hypothyroidism 
No h/o fever, nausea, vomiting 
No h/o loss of appetite or weight loss
No h/o sleep disturbances 
Bowel and bladder habits regular.

DIAGNOSIS: SOLITARY THYROID NODULE

ON [19/3/2023]
PT REFERRED TO GEN MED I/V/0 SHORTNESS OF BREATH AND IRRITABILITY SINCE TWO DAYS.
 
Hopi:
No h/o bone pain, cough, hemoptysis, jaundice, abdomen fullness, headache and seizures. 
 
Past history:
H/o hyperthyroidism since 11years
Surgical history of Right hemithyroidectomy 6 years back
H/o hysterectomy done 40 yrs ago
Not a k c o Hypertension, CAD, TB, asthma, epilepsy. 

PSYCHIATRY REFERRAL: 

C/O 
INCREASED IRRITABILITY 
Unability to recognise family members 
Abnormal behaviour in the form of moaning and incoherent sounds , trying to get up and leave 
Pts sleep decreased, appetite decreased 
Self care and hygiene maintained by od.
Not able to do regular daily activities due to physical illness.

Hopi:
No h/o head injury, seizure activity 
No h/o blood in vomiting/ stool
No h/o pervasive low moods, easy fatiguability or suicidal ideations
No h/o palpitations, fearfulness or feeling of impending doom
No h/o grandiose or flight if thoughts
No h/o repetitive thoughts or actions

Past history 
H/o alcohol consumption since 30 years [initially toddy currently whiskey][consumption amounts accurately not known]

Family History: no significant psychiatric illness in family

MSE: pt sitting on the bed awake and alert but not responding to her name. pt is restrained to the bed (soft restrain) . 
Thin built , cannula in place
Enterotoxigenic E. coli (ETEC) + not maintained
Psychomotor agitation increased
Speech - incoherent and decreased 
Mood/Affect - agitated and IRRITABILITE 
Thought and perception- cnbe
Not oriented to time place and person 

* delirium due to general medical condition * 

psychiatric Treatment plan 
1.Tab pregabalin 75mg
2.tab oxazepam 15mg po/sos
 Personal History:
DIET: MIXED 
APPETITE: NORMAL 
BOWEL AND BLADDER MOVEMENTS: REGULAR 
SLEEP: ADEQUATE 
ADDICTIONS: NO

Family History: 
H/o thyroid swelling malignancy in father.

Treatment history:
 CARBIMAZOLE 10mg po/bd
 Salbutamol for dyspnea 

Menstrual History
Menarche 11 years
Age at marriage 15 years
Age at 1st child born 18years
Menopause at 45 years

General Examination 

O/e Pt is c/c/c
Oriented to time place and person
Temp : 97.4
Pr : 84/min
BP: 130 /80 mmhg
Spo2 : 98% on RA
Cvs : s1s2+ no murmurs 
RS : bae+ ,nvbs
Moderately built and nourished 
Texture of skin - normal
Hair - Normap
Exophthalmos -present
Tremors - present
No signs of pallor,icterus, cyanosis,lymphadenopathy & pedal edema 

Local examination 
 
On inspection 
A 8x6cm Solitary vertically oval swelling seen on left side of neck.
Extending superiorily above thyroid bone.
Inferiorly beyond the suprastwrnal notch 5cm away from right sternocleidomastoid 
Engorged veins present 
 A transverse scar of 3x1cm present at right side of neck
Skin over swelling NORMAL
smooth surface
Borders are well defined 
Swelling moves up&down with deglutation
No visible pulsations
Lower border of swelling visible
Trachea appears to be deviated to right side
No other swellings in neck 
No discolouration or erythema

Palpation: 
No local rise of temperature 
No tenderness
All inspectory findings confirmed
Surface is smooth,
Hard in consistency 
Restricted mobility 
KOSHERS NEGATIVE - 
Carotid pulsations fast on both sides
NO PALPABLE THRILL,
NO PALPABLE CERVICAL LYMPH NODES

Auscultation 
No resonant note over manubrium sternum

Percussion 
Bruit heard

DIAGNOSIS 
Altered sensorium secondary to 
?Hyponatremia ?uremia
?Aki on ckd
Solitary thyroid nodule 2° to hyperthyroidism 
Hypercalecimia and hyperkalemia secondary to CKD
Heart failure with mid range ejection fraction

Treatment
1.Iv fluids 0.9% NS @ 50ML/hr
2.INJ lasix 20mg iv/od
3. Tab ECOSPRIN 75/10 p0/od
4. Tab nodosis 500mg po/bd
5. TAB CARBIMAZOLE 20mg po/bd
6. Tab propanolol 20mg po/bd
7. Strict I/O monitoring 
8. GRBS MONITORING 6TH HOURLY 
9. Vitals 4th hrly 
10. TAB AMLONG 5mg po/only after informing respective Dr's.

25/4/2023
Amc bed 3

S
No Fever spikes
Stools passed

O
Pt is c/c/c
Oriented to time place and person
Temp : 98.3
Pr : 86/min
BP: 130 /70 mmhg
Spo2 : 98% on RA
RR : 18/min
Cvs : s1s2+ no murmurs 
RS : bae+ ,nvbs
Cns : NAD 
GCS: E4V5M6
P/A : soft, non tender 

A
Altered sensorium secondary to 
?Hyponatremia (resolved)
?uremia
?Aki prerenal (resolved)
Solitary thyroid nodule 2° to hyperthyroidism 
Hypercalecimia and hyperkalemia secondary to RF
Heart failure with REDUCED ejection fraction (35%)
S/P RT. HEMITHYROIDECTOMY 15YRS BACK WITH HTN

P


1.. Tab ECOSPRIN AV 75/10 p0/od
2. TAB CARBIMAZOLE 20mg po/bd
3. Tab propanolol 20mg po/bd
4. Tab DYTOR 20mg po/bd
5. NODOSIS. 500MG PO/BD
6. OINT. THROMBOPHOBE LA/TID
7. GRBS MONITORING 6TH HOURLY 
8. Vitals 4th hrly 

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